DISCRIPTION :-
PHARMACEUTICAL ORGANIC CHEMISTRY :-
IV Semester Examination May 2019
BACHELOR OF PHARMACY
Pharmaceutical Organic Chemistry - 3
(BP-401T)
Time :- 3 hrs. Marks :- 80
Answer any FIVE questions :-
1. a) Explain the various elements of symmetry in detail with the suitable examples. (8)
b) What is the Racemic Mixture and the Meso compounds? How will you perform the resolution of the racemic mixture ? (8)
2. a) Explain the methods of determination of configuration of the geometrical isomers. (8)
b) Discuss the various conformational isomers of the Cyclohexane with its energy levels. (8)
3. a) Describe the chemical reactions, synthesis and the medicinal uses of Furan. (8)
b) Write about the reactivity and relative aromaticity of pyrrole. (8)
4. a) Describe about the chemical reactions, synthesis and uses of Quinoline. (8)
b) Describe about the chemical reactions, synthesis and uses of Pyrimidine. (8)
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5. a) Discuss the Birch reduction with its mechanism and the synthetic importance. (8)
b) How will you determine the configuration of the Oximes by Beckman rearrangement ? (8)
6. a) Distinguish Enantiomers and Diasteromers with the suitable examples. (8)
b) Write the short notes on atropisomerism with Kaufler's Butterfly model. (8)
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7. a) Discuss the chemical reactions, synthesis, medicinal uses and basicity of Pyridine. (8)
b) What is Wolff Kishner reduction ? Explain about the reaction of the synthetic importance. (8)
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