I Semester Examination December 2017
BACHELOR OF PHARMACY
Pharmaceutical Inorganic Chemistry
(BP-104T)
Time :- 3 hrs. Marks :- 80
Answer any FIVE questions :-
1. a) What are the various measures to minimize impurities in pharmaceuticals ? Why is quantification of impurities considered necessary in pharma-ceuticals? (8)
b) Why limit tests are essential for pharma ceuticals? Write down the principle and chemistry of limit test of Lead. (8)
2. a) Give an account of buffer systems used in the preparation of pharmaceuticals. What are the various methods of calculating isotonicity? (8)
b) Write down the composition of ORS as per WHO guidelines with a brief description of functions of each electrolyte. (8)
3. Write down short note on following (any four): (16)
a) Dentifrices
b) Buffer capacity
c) Cathartics
d) Haematinics
e) Poison and Antidotes
4. a) Define radioactivity. Compare various forms of radiations. Write down the storage conditions for radiopharmaceutical preparations. (8)
b) What are emetics ? Write down the method of preparation and assay of copper sulphate. (8)
5. a) Briefly describe antimicrobial agents and its classification. Write down the methods of preparations, assay and uses of Hydrogen peroxide. (8)
b) What are expectorants ? How they differ from antitussive agents? Give method of preparation and assay of ammonium chloride. (8)
6. a) Enlist the properties of an ideal antacid. Write the methods of preparation and medicinal uses of Sodium bicarbonate. (8)
b) Write the detailed account of desensitizing agents with their applications. (8)
7. Write down the methods of preparation and uses of the following (any four): (16)
a) Calcium Gluconate
b) Ferrous Sulphate
C) Chlorinated lime
d) Sodium Thiosulphate
e) Sodium Chloride
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