II Semester Examination May 2019
BACHELOR OF PHARMACY
Biochemistry
(BP-203T)
Time :- 3 hrs. Marks :- 75
Answer any FIVE questions :-
1. Explain any two :- (7.5 × 2 = 15)
a) Citric acid cycle and its energetic
b) HMG shunt and its significance
c) Gluconeogenesis
2. Explain briefly any two :- (7.5 × 2 = 15)
a) Biological significance of ATP and cAmp.
b) Electron transport chain and its mechanism.
c) Hormonal regulation of blood glucose level.
3. Write short notes on any three :- (3 × 5 = 15)
a) Protein synthesis and inhibitors
b) Biosynthesis of purine nucleotides
c) DNA replication (semi conservative model)
d) Hyperucemia and Gout disease
e) Hyperbilirubnemia
4. a) Define the term Ketoacidosis. Briefly explain formation and utilization of ketone bodies. (7.5)
b) Describe B-oxidation of saturated fatty acid (Palmitic acid). (7.5)
5. Write down the conversion of cholesterol into bile acids and steroid hormone. (15)
6. Explain any two :- (7.5 × 2 = 15)
a) Synthesis and significance of Noradrenaline
b) Urea Cycle and its disorders
c) De novo synthesis of Palmitic acid
7. a) Write down in detail about Enzyme kinetics (Michaelis plot and Line Weaver Burke plot). (7.5)
b) Describe structure and biochemical function of Coenzymes. (7.5)
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